A naturally occurring flavonoid chemical belonging to the Lacqueraceae family that is derived from plants like wood wax is called lacquerin, or Fisetin powder. Fruits and vegetables also contain lacquerin, which has pharmacological qualities including anti-inflammatory and antioxidant capabilities.
In terms of raw material selection, from the perspective of green environmental protection, sustainability, and economic practicality, select the branches and leaves of Cotinus coggygria, as well as the discarded stems in the process of returning farmland to forests. By carefully screening the leaves and branches of Cotinus coggygria from different regions and periods, the QY team identified the most suitable period for picking Cotinus coggygria branches and leaves.
In terms of the extraction method, the continuous countercurrent extraction method is adopted. Can make the crushed raw materials of Cotinus coggygria come into full contact with the solvent. The use of continuous countercurrent can ensure a high throughput of raw materials while also ensuring efficient extraction; The use of water solvents can make the production process more environmentally friendly, safe, and economical. The residue extracted through continuous countercurrent extraction can be used for plant composting, reflecting QY's green and environmentally friendly concept.
Due to the decomposition of quercetin into other substances at high temperatures, too low a temperature is not conducive to the extraction of quercetin. Therefore, after multiple attempts, the QY team found the most favorable temperature for the extraction of quercetin and can use the most economical and practical extraction conditions to maximize the extraction of quercetin from sumac.
Certificate of Analysis:
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Item |
Specification |
Result |
Method |
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|
Assay |
Fisetin 95%(External standard method) Fisetin98%(Normalization method) Fisetin 98% |
95.17% 99.08% |
HPLC |
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|
Physical & Chemical Data |
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Appearance |
Yellow Fine Powder |
Conforms |
Organoleptic |
|
|
Odor & Taste |
Characteristic |
Conforms |
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|
Analytical Quality |
||||
|
Identification |
Identical |
TLC |
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Sieve |
NLT 95% Through 80 mesh |
Conforms |
Mesh Screen |
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|
Extract Solvent |
Ethanol & Water |
Conforms |
||
|
Loss on Drying |
≤5.0% |
0.13% |
CP2020 |
|
|
Ash |
≤5.0% |
1.27% |
CP2020 |
|
|
Bulk Density |
0.30~0.70g/ml |
Conforms |
CP2020 |
|
|
Pesticide Residue |
||||
|
BHC |
≤0.2ppm |
Conforms |
GC-MASS |
|
|
DDT |
≤0.2ppm |
Conforms |
GC-MASS |
|
|
PCNB |
≤0.1ppm |
Conforms |
GC-MASS |
|
|
Total Heavy Metals |
≤10ppm |
Conforms |
Colorimetry |
|
|
Arsenic(As) |
≤2ppm |
Conforms |
AAS |
|
|
Lead(Pb) |
≤2ppm |
Conforms |
AAS |
|
|
Mercury(Hg) |
≤0.1ppm |
Conforms |
AAS |
|
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Cadmium(Cd) |
≤1ppm |
Conforms |
AAS |
|
|
Microbiological Tests |
Irradiation |
Non irradiated |
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|
Total Plate Count |
≤1000cfu/g |
≤10000cfu/g |
Conforms |
CP2020 |
|
Yeast & Mold |
≤100cfu/g |
≤300cfu/g |
Conforms |
CP2020 |
|
E.Coli |
Negative |
Negative |
Negative |
CP2020 |
|
Salmonella |
Negative |
Negative |
Negative |
CP2020 |
|
Staphylococcus |
Negative |
Negative |
Negative |
CP2020 |
|
Conclusion |
Conform with specification |
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What's Main Function of Fisetin powder?
(1) Delaying aging: Lacquer flavin, an effective senolytic agent, can help the body eliminate aged cells and postpone aging. Aging cells progressively build up with age, harming other cells and resulting in long-term bodily damage, therefore hastening the aging process. Quercetin is the flavonoid that has the greatest capacity to eliminate aged cells out of all the flavonoids that were studied.
(2) Turning on longevity factors: Longevity factors are a special group of proteins that have the capacity to control cell viability and increase longevity. According to research, lacquer flavin can activate longevity factors and increases fruit fly lifetime by 1.2 times.
Blocking Aging Factors (mTOR): Aging is intimately correlated with mTOR. It has been demonstrated that using mTOR inhibitors increases longevity and offers protection.
(4) Fisetin powder can remove free radicals and enhance the level of glutathione. Fisetin can directly eliminate free radicals and enhance the level of glutathione, which may help regulate the production of many proteins involved in protecting the body from oxidative stress and maintaining redox homeostasis. This is the mechanism by which glutathione achieves its antioxidant effect.
(5)It also has anti-tumor effects. In vitro studies have shown that it has effects against human lung cancer cells, uterine cancer cells, human skin cancer cells, and human colon cancer cells. Its main mechanism is to induce organ differentiation of cancer cells by modifying cancer cell genes, transforming them into normal cells.
(6)It has unique effects on brain health, cognition, and memory. Most of the research in this area has been conducted at the renowned Salk Institute for Biological Studies in San Diego, focusing on studying it as a "smart substance" and "neuro-nutrient factor". As mentioned earlier, it can cross the blood-brain barrier and exert a "pruning" effect, removing aging cells and replacing them with healthy cells, eliminating old, useless, or potentially harmful cells. Some believe that it has twice the ability of quercetin to do so.
What is our advantage?

1. Currently, we have two factories. A GMP implementation standard factory with a 100,000-level purification workshop, and a fine processing workshop covering an area of 400 square meters.
2. Now we have Halal/kosher/SC/ISO9001/ISO22000 certificate
3. The professional team will provide you with perfect after-sales service.
4. Professional laboratories provide you with various tests.
5. Customize production for customers according to customers' quality and price of products.

What we can do for you?

1.OEM SERVICE(tablets, capsules soft capsules)
2.Purchasing service(API IngredInts, Amino Acld,vitamIn))
3. TESTING
4. INFORMATION.
How to contact you?
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Sales Market: |
Email: sales@dnbiology.com |
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President's Office |
Email: info@dnbiology.com |
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