1.Application in medicine
(1) Amino acid infusion is one of the aspects with the largest amount of L-Arginine 99% Powder
At present, its main clinical uses include: improving the nutritional status of patients before surgery, so that large-scale surgeries can be carried out smoothly; providing protein nutrients for patients with gastrointestinal diseases and digestive and absorption disorders; replenishing the serious loss of proteins in wounds, burns, bone fractures, septicemia and postoperative period; correcting the disorders of biochemical synthesis of proteins caused by liver cirrhosis and liver disease; preventing and treating leukopenia caused by radiation, anticancer agents or other reasons; saving blood as a plasma substitute. Biochemical synthesis disorders; prevention and treatment of radioactivity, anticancer agents or other causes of leukopenia; as a plasma substitute for the use of blood, saving blood and other aspects. China's crystalline amino acid infusion agent development speed is amazing, in 1985 for 1 million bottles, 1990 15 million bottles, 1993 50 million bottles, 2000 150 million bottles, 2002 200 million bottles; in 2007 the national pharmaceutical use of L-arginine amount of 1,585 tons in 2008 is higher than 1,900 tons in 2012 is expected to be more than 3,300 tons. At present, the medical market, some drugs such as cefradine injection, its pH is very low, about 3.0 ~ 3.5, in the past, add sodium bicarbonate as a neutralizing agent is easy to produce CO2 bubbles in blood vessels, affecting vascular smoothness, now as a neutralizing agent and at the same time increase the nutrients, only this one, the domestic demand for more than 300 tons / year.
(2) Other arginine preparations
Arginine succinate is a strong liver tonic, conducive to the growth and development of the liver, the liver tissue to play a role in rehabilitation, "polyammonia blood" to alleviate the role; can also promote protein synthesis. Arginine glucuronide with anti-fatigue, detoxification and energy; and reduce blood ammonia and tissue ammonia, can also be used to increase bile secretion and enhance liver metabolism, arginine maleate; as well as arginine glutamic acid, arginine aspartic acid, in vivo can play a synergistic effect of the two amino acids, of which the latter can reduce fatigue, treatment of neurasthenia, insomnia, memory loss, and other symptoms, and non-toxicity; in addition, phosphorus glucose is a hepatoprotective drug, which is beneficial to liver growth and development, and has a relieving effect on "polyammonia"; can also promote protein synthesis. Arginine is a hepatoprotective drug, can promote stem cell regeneration, hepatotoxicity and hyperammonia have therapeutic effects, delirium tremens have significant curative effects. In addition, the compound preparation of arginine and deoxycholic acid, known as minoxifen, can effectively treat syphilis and viral jaundice. There are some arginine derivatives such as arginine keto typhon will be used in large quantities in the clinic, will undoubtedly increase the demand for L-arginine.
2. L-Arginine 99% Powder in animal husbandry applications
L-arginine is infants (young animals) and fish essential amino acids, and in 1999 the Japanese Ministry of Agriculture, Forestry and Fisheries promulgated L-arginine as a new feed additives with amino acids, together with other amino acids, not only to supplement the nutrients, but also to improve the physiological function of the object of feeding, to improve the survival rate of young animals, to promote the growth of young animals. Take piglets as an example, the demand for it is very high. Breast milk contains 1.34 g/L, which only meets 40% of the demand of piglets, and its shortage will inhibit the growth performance of piglets.
The U.S. feed standard stipulates that a certain amount of arginine should be added to the feed for chicks and laying hens. In addition, it can be used to improve the female rate of livestock in addition to being used as feed in the animal husbandry industry. In some domestic and international reports, the treatment of dairy cows prior to fertilization can effectively increase the female production rate of dairy cows. This research finding is expected to realize more females and fewer or no males, which is of great significance in accelerating the development of cow dairy industry.
3.Arginine in food and beverage applications
L-arginine can be used as food additives with anticorrosive and anti-inflammatory properties and no toxicity itself. In addition, because it has the characteristics of hypoxia resistance and anti-fatigue, it can be made into functional food to improve the overall quality of athletes and soldiers in the current market, the beverage companies are competing to add amino acids to the drinks.
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