What is GHK-Cu used for?

In recent years, in the skincare product category, apart from the commonly seen VA, VC, and 377, a dark horse has emerged-GHK-Cu Powder, known as "soft gold," which is hailed for its anti-aging repair, antioxidant capabilities, and its ability to inhibit inflammation.

What do copper peptides do in cosmetics?

① What does GHK-Cu Powder do for skin?

In 1999, Maquart et al. first demonstrated that Copper Tripeptide modulates various metalloproteinases in the skin reconstruction process of rats. The action of these enzymes helps separate extracellular grid proteins, and it can adjust the corruption of extracellular framework proteins (ECM proteins) to forestall over the top skin harm. Of particular interest is that Copper Tripeptide increases the core proteoglycans, whose function is to regulate the assembly of collagen fibrils, prevent scar formation, and reduce the levels of transforming growth factor (TGF-beta), which can increase scarring.

Besides, Copper Tripeptide aids the appearance of resistant and endothelial cells at the site of injury, which is one more justification behind its part in advancing injury recuperation. As of now, numerous creature tests have likewise affirmed the injury-recuperating viability of Copper Tripeptide.

②Do copper peptides increase collagen?

Experiments have shown that Tripeptide stimulates the synthesis of collagen, selective glycosaminoglycans, and small proteoglycans.

Furthermore, it can regulate the synthesis of related metalloproteinases, some of which exacerbate the breakdown of extracellular matrix proteins, while others are enzymes that can inhibit protease activity.

This suggests that Copper Tripeptide has a regulatory effect on protein levels in the skin.

③Does GHK-Cu reduce inflammation?

Inflammation is always accompanied by an increase in oxidative damage, one of the reasons being that immune cells use reactive oxygen species (ROS) and other powerful oxidants (such as hypochlorous acid and peroxynitrite) to combat bacteria and damage.

Research has shown that GHK-Cu Powder reduces inflammation by reducing the levels of acute-phase inflammatory cytokines such as TGF-beta and TNF-alpha.

Tripeptide-1 also reduces oxidative damage by regulating iron levels and quenching the toxic byproducts of fatty acid lipid peroxidation.

Since lipid peroxidation plays a significant role in skin aging and UV-induced skin damage, the ability of Tripeptide-1 to form complexes and isolate the toxic byproducts of lipid peroxidation has a protective effect against skin aging and photodamage.

One use of Copper Tripeptide is in sunscreen cosmetics.

Many synthetic compounds that reduce UV rays can lead to the formation of free radicals, increasing oxidative damage to the skin.

Adding Copper Tripeptide-1 to sunscreen cosmetics can reduce the levels of harmful byproducts of lipid peroxidation, reducing inflammation and skin damage.

④Promotion of Wound Healing

Numerous animal studies have confirmed the wound healing abilities of Copper Tripeptide. In rabbit experiments, Copper Tripeptide can accelerate wound healing and promote angiogenesis, increasing the content of antioxidant enzymes in the blood. This molecule also promotes wound healing in rats, mice, and pigs.

⑤ Copper Tripeptide and Skin Stem Cell Regeneration

Skin regeneration is dependent on the viability and proliferative capacity of skin stem cells. In cell culture, Copper Tripeptide-1 (0.1-10nM) stimulates the proliferation of keratinocytes in a dose-dependent manner and there is no toxicity at these concentrations. The addition of Copper Tripeptide-1 leads to significant changes in epidermal basal cells, with a marked increase in the expression of integrins and a tumor suppressor gene (p63), which indicates increased stem cell activity in basal keratinocytes. Researchers have concluded that Copper Tripeptide can maintain the stem cell activity of basal keratinocytes and restore their proliferative potential.

The ability of GHK-Cu to restore the proliferative potential of epidermal stem cells makes it a crucial component in the process of skin repair and rejuvenation.

⑥GHK-Cu Can Restore the Function of Damaged Cells

Fibroblasts are the primary cells for wound healing and tissue regeneration. They not only synthesize various components of the extracellular matrix but also produce a large number of growth factors (which regulate cell migration, proliferation, angiogenesis, etc.).

However, fibroblasts are sensitive cells that can be damaged by various factors, such as radiation that can damage cellular DNA.

A study in 2005 showed that Tripeptide-1 can restore the vitality of fibroblasts damaged by radiation.

Clinical Evidence: The Anti-Aging Effects of GHK-Cu Powder are Significant.

The results of clinical experiments have proven that skincare products containing Copper Tripeptide-1 have the following effects:

(1) Firming the skin and improving elasticity.

(2) Increasing skin density and toughness.

(3) Reducing fine lines and deep wrinkles.

(4) Enhancing skin brightness.

(5) Reducing pigmentation and spots.

(6) Significantly improving keratinocyte proliferation.

Qyherb, a leading manufacturer and supplier of GHK-Cu Powder in China, is renowned for its professional service and competitive prices.

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