What Makes Vitamin K2 MK-7 So Beneficial?

Feb 26, 2024Leave a message

Vitamin K2 MK-7 is a fat-soluble vitamin and a derivative of naphthoquinone with phytol side chains, mainly found in fermented foods, that participates in calcium metabolism. It can be further classified into MK-4 to MK-13 based on the number of isoprenoid units in the side chain. Although the forms of vitamin K2 are similar, their structures differ greatly. Recent research shows that vitamin K2-MK7 is the most bioavailable version that is more easily absorbed and remains active longer in the body, making it the most efficacious type.

Mechanism of Action of Vitamin K2 MK-7

It provides guidance for calcium to precisely enter the bones, teeth and other body areas that require it, rather than going astray in the bloodstream. Nicknamed the "platinum vitamin", K2 MK-7 has the dual functions of regulating calcium deposition and removing misplaced calcium deposits. It effectively activates the matrix Gla protein and osteocalcin, reducing calcium deposition in soft tissues like blood vessels, inhibiting vascular calcification, and preventing cerebrovascular diseases, while also mobilizing calcium for accurate relocation into bones, promoting osteogenesis and inhibiting osteoporosis for enhanced bone health.

Vitamin K2 MK-7

Health Benefits:

Vitamin K2 MK-7 was first approved in Japan as a treatment for osteoporosis and was subsequently approved in the U.S., E.U., and other countries as a nutritional supplement. In 2016, China also officially included it in the health food raw materials catalog, adding it as a new nutritional fortification ingredient. As the gold standard form of vitamin K2, what makes MK-7 so beneficial? Let's explore:

- Prevents vascular calcification that can induce arteriosclerosis, atherosclerosis, heart disease, myocardial infarction, and other cardiovascular disorders.

- Plays an important role in preventing renal vascular calcification, and kidney stones and improving glomerular filtration rate for kidney health. It also helps activate inactive MGP proteins in dialysis patients to reduce mortality from vascular calcification.

- Protects brain cells and inhibits cerebral vascular calcification to prevent senile dementia, strokes, and other cerebrovascular diseases.

- Activates osteocalcin for new enamel formation, reducing cavities and slowing dental aging.

- Bone growth is most active in childhood and adolescence, with peak bone mass reaching 90% of maximum by ages 18-20. Children and teenagers need 8-10 times more osteocalcin than adults for calcium absorption and bone building. Vitamin K2 promotes calcium absorption to help build stronger bones in kids and teens, preventing osteoporosis later in adulthood.

Differences Between Natural and Synthetic Vitamin K2

For selecting vitamin K2, what are the differences between natural fermented and chemically synthesized forms?

- Synthetic MK-7 uses toxic solvents or chemical catalysts in production, which may impact efficacy and be difficult to fully remove, posing residual risks.

- Natural fermented MK-7 utilizes Bacillus subtilis natto bacteria and supercritical CO2 extraction. As the TRANS-type, it activates the bioactive form of vitamin K2.

Differences Between Natural and Synthetic Vitamin K2

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