At present, a variety of functional products containing Grape Seed Extract Powder have appeared in the domestic and foreign markets. There is a problem of too much or too little of the functional components of grape seed proanthocyanidin products. The following is the recommended daily dosage of grape seed extract OPC.

OPC Overview
The main component of grape seed extract is grape seed proanthocyanidins. Grape seed proanthocyanidins take catechin and epicatechin as the unit. It is formed by bonding C4-C8 (linear) or C4-C6 (branch). The average degree of polymerization reaches 2.4 to 16.7. According to the degree of polymerization, two to pentamers are usually referred to as oligomeric procyanidins (OPC), and those above pentamers are referred to as high polymeric procyanidins (PPC).
Proanthocyanidins have a variety of biological activities, such as anti-oxidation, anti-radiation, protection of the cardiovascular system, etc. Proanthocyanidins with different degrees of polymerization have different biological activities, among which oligomeric proanthocyanidins are easily absorbed by the human body and can exert their biological efficacy.
Grape Seed Extract Dose
The active ingredient in grape seed extract is grape seed proanthocyanidins. The content and daily dosage of proanthocyanidins in each health food are different. This is because, on the one hand, different detection methods of grape seed polyphenol procyanidins affect the determination of the amount of procyanidins. On the other hand, the dosage of proanthocyanidins varies among different health-care functions. At present, there is no clear regulation on the dosage of grape seed proanthocyanidins in the world. The general recommended dosage for dietary supplements in European and American countries is 100-300 mg/d. According to Japanese recommendations, the recommended daily dosage for various symptoms is as follows.
Symptom | Function | Dosage/(mg/d) |
Venous Aneurysm | Improve Symptoms | 150~300 |
Diabetic Retinal Variation | Improve The Retina | 100~150 |
Diabetes, High Blood Pressure | Improve Capillary Resistance | 100 |
Arteriosclerosis | Prevention | 100 |
Cancer | Prevention | 100 |
Alzheimer's | Prevention | 100 |
Muscle Fatigue | Prevention | 180 |
Lipid Peroxidation | Prevention | 200 |




