Urolithin A Powder

Urolithin A Powder

Appearance: Beige to yellow powder
Active Ingredient:≥98%
MOQ:1KG
Production capacity (monthly): 200 kg
Testing Method: HPLC
CAS:1143-70-0
Sample:5-10g(free))
Package: 1kg/bag, 5kg/bag, 25kg/drum
Grade: Food Grade
Certificate: ISO, KOSHER, HALAL/GMP/HACCP
Delivery date: 3-5 days by Express

Product Introduction

Product Introduction

Urolithin A  powder is a naturally occurring compound that is produced by the gut microbiota when it digests ellagitannins. Ellagitannins are a type of polyphenol that is found in various species of fruits, nuts, and other plant-based foods. Urolithin A has been found to have numerous health benefits, including anti-inflammatory properties, anti-cancer effects, and the ability to enhance mitochondrial function.

 

The discovery of urolithin A as a potential health supplement came from research into the health benefits of pomegranates. Scientists discovered that when people consumed pomegranates, a small percentage of them would produce large amounts of urolithin A. Since then, research has focused on the benefits of urolithin A and how it can be used to promote health and longevity.

Urolithin A  powder

 

Cosmetic Functions

One of the most significant health benefits of urolithin A is its ability to improve mitochondrial function. Mitochondria are the structures within cells that are responsible for generating energy from food. As we age, mitochondrial function can decline, leading to a range of chronic health conditions. Studies have shown that urolithin A can activate a process called mitophagy, which is the natural way that cells clear out and remove damaged mitochondria. By promoting mitophagy, urolithin A can help to enhance mitochondrial function and reduce the risk of age-related diseases.

 

Another health benefit of urolithin A is its anti-inflammatory properties. Chronic inflammation can contribute to a range of health problems, from heart disease to Alzheimer's disease. Urolithin A has been found to inhibit the production of pro-inflammatory cytokines, which are molecules that promote inflammation in the body. By reducing inflammation, urolithin A can help to prevent chronic disease and promote overall health and wellbeing.

 

Research has also shown that urolithin A has anti-cancer effects. In laboratory studies, urolithin A has been found to induce cell death in various types of cancer cells, including breast, prostate, and colon cancer. Urolithin A has also been shown to inhibit the growth and proliferation of cancer cells. While further studies are needed to determine the full extent of urolithin A's anti-cancer effects, these initial findings are promising.

 

Urolithin A is available as a dietary supplement in capsule form and as an ingredient in functional foods and beverages. However, it is important to note that more research is needed to determine the optimal dosage and safety of urolithin A. As with any supplement, it is important to speak with a healthcare professional before adding urolithin A to your diet.

 

Certificate of Analysis:

Item

Specification

Result

Assay

≥98.0%

99.08%

Appearance

Beige to yellow powder

 

Conforms

Analytical Quality

Identification

1HNMR confirms to structure

 

Conforms

 

LCMS

 

LCMS Conforms to MW

 

Conforms

 

Water

≤0.5%

 

0.26%

Residual Solvents

Methanol

 

≤3000ppm

 

Conforms

TBME

 

≤1000ppm

 

Conforms

Toluene

 

≤890ppm

 

Conforms

DMSO

 

≤5000ppm

 

Conforms

Acetic Acid

 

≤5000ppm

 

Conforms

Total Heavy Metals

 

Arsenic(As)

≤1.5ppm

Conforms

Lead(Pb)

≤0.5ppm

Conforms

Mercury(Hg)

≤0.1ppm

Conforms

Cadmium(Cd)

≤0.5ppm

Conforms

Conclusion

Conform with specification

 

HPLC Testing:

HPLC Testing:

qyherb HPLC Testing

 

High-performance liquid chromatography (HPLC) is a commonly used analytical technique for testing the presence and quantity of urolithin A in a sample. HPLC separates, identifies, and quantifies the individual components of a sample mixture.

To perform HPLC testing for urolithin A, a scientist would first extract the compound from a food or supplement sample using a suitable solvent. The extracted solution would then be filtered to remove any impurities and prepared for analysis.

Next, the prepared sample would be injected into an HPLC system equipped with a column designed to separate the components of the sample. The urolithin A would be separated from other compounds in the sample based on its unique physicochemical properties such as size, solubility, and charge.

As the sample components pass through the column, they are detected by a UV detector, which measures the absorbance of the sample at a specific wavelength. Based on the data obtained, scientists can calculate the amount of urolithin A present in the sample.

HPLC is a highly sensitive and precise technique that is widely used in research and industry for the analysis of natural products like urolithin A. It is important to note that proper sample preparation and calibration of the HPLC system are essential to obtain accurate results.

 

HNMR Testing:

 

HNMR Testing

Proton nuclear magnetic resonance spectroscopy (HNMR) is another technique that can be used to test the presence and purity of urolithin A in a sample. HNMR is based on the principle of nuclear magnetic resonance, which exploits the spin properties of atomic nuclei.

To perform HNMR testing for urolithin A, a purified sample of the compound is dissolved in a suitable solvent and placed in an NMR spectrometer. The spectrometer exposes the sample to a strong magnetic field and radiofrequency waves, causing the atomic nuclei to absorb and emit electromagnetic radiation.

A detector in the NMR spectrometer measures the energy absorbed and emitted by the atomic nuclei and generates a spectrum that represents the chemical structure of the molecule. The spectrum provides information about the number and type of atoms present in the molecule, as well as their chemical environment and the bonding between them.

By comparing the spectrum obtained from the sample to reference spectra of known compounds, scientists can confirm the identity and purity of urolithin A in the sample. HNMR is a powerful technique that can provide detailed structural information about small molecules like urolithin A with high accuracy and precision.

 

What’s the Key Function of Urolithin A Powder?

 

1. Anti-inflammatory: Urolithin A has been found to possess anti-inflammatory properties, which may help reduce inflammation in the body. Chronic inflammation has been linked to a range of health problems, including cardiovascular disease, diabetes, and cancer.

 

2. Antioxidant: Urolithin A is a potent antioxidant that helps to neutralize free radicals and reduce oxidative stress in the body. Oxidative stress is a condition that occurs when there is an imbalance between the production of reactive oxygen species (ROS) and the body's ability to detoxify them. This condition has been linked to aging and the development of various diseases.

 

3. Mitochondrial health: Urolithin A has been shown to activate mitophagy, a process by which damaged or dysfunctional mitochondria are eliminated from cells. This process may help to improve mitochondrial function and reduce oxidative stress in cells, which can help maintain cellular health and prevent age-related diseases.

 

4. Muscle health: Urolithin A has been found to stimulate the production of new mitochondria in muscle cells, which can help improve muscle function and reduce muscle wasting associated with aging, disease, or physical inactivity.

 

5. Neuroprotective: Urolithin A powder has been shown to protect neurons against damage caused by toxic proteins, such as beta-amyloid and tau, which are associated with Alzheimer's and other neurodegenerative diseases. This neuroprotective effect may offer potential benefits for brain health and cognitive function.

 

Cosmetic Functions

 

1. Antioxidant: Benfotiamine can help resist damage caused by free radicals and exhibit excellent antioxidant effects on the skin.

 

2. Reducing Pigmentation: Benfotiamine can inhibit the production of melanin and reduce pigmentation.

 

3. Moisturizing and Whitening: Benfotiamine can promote the moisturization of the skin and improve skin tone, making it an important component in many cosmetics.

 

What is our advantage?

why choose us

1. Currently, we have two factories. A GMP implementation standard factory with a 100,000-level purification workshop, and a fine processing workshop covering an area of 400 square meters.

2. Now we have Halal/kosher/SC/ISO9001/ISO22000 certificate

3. The professional team will provide you with perfect after-sales service.

4. Professional laboratories provide you with various tests.

5. Customize production for customers according to customers' quality and price of products.

certificate

What we can do for you?

Service

1.OEM SERVICE(tablets, capsules soft capsules)

2.Purchasing service(API IngredInts, Amino Acid,vitamIn))

3. TESTING

4. INFORMATION.

 

How to contact you?

Sales Market:

Email: sales@dnbiology.com

President's Office

Email: info@dnbiology.com

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