Natural Lycopene Powder, also known as tomato red pigment, is a naturally occurring red open-chain hydrocarbon carotenoid found in plants. It was first isolated and extracted from tomatoes, hence the name "lycopene." It is a needle-shaped deep red crystal with a chemical structure consisting of 11 conjugated double bonds and 2 non-conjugated double bonds, forming a linear hydrocarbon compound, which has different physiological capabilities, like free extremist rummaging, dialing back atherosclerosis, improving the insusceptible framework, and safeguarding the skin. Lycopene has been delegated a sort A supplement by the World Wellbeing Association, the Joint FAO/WHO Master Panel on Food Added Substances, and the Food and Farming Association of the Unified Countries.
Health Benefits of Natural Lycopene Powder
01. Research in the direction of antioxidant activity
Lycopene is perhaps the most grounded cell reinforcement tracked down in nature, with a prevention agent limit multiple times that of vitamin E. Studies have shown that controlling lycopene to female mice at a portion of 30 mg/kg for 4 sequential days (twice/day) essentially expanded the exercises of Grass, GSH-Px, and Feline in serum, while decreasing MDA levels, demonstrating that lycopene's cell reinforcement impact in the body is connected with the enactment of endogenous prevention agent protein frameworks. Peng Liang et al. investigated the cell reinforcement impact of lycopene on the human body, and the outcomes showed a critical reduction of 11.03% in serum malondialdehyde content, a 6.80% increment in superoxide dismutase movement, and a 11.74% expansion in glutathione peroxidase action in the preliminary gathering contrasted with the benchmark group, exhibiting huge prevention agent impacts of lycopene on the human body.
02. Research on various models
Lycopene can block the damage of free radicals to cellular DNA and reduce the risk of carcinogenesis. Several epidemiological studies have shown that populations with high lycopene intake have lower risks of health issues compared to the general population. Studies by Rowles et al. revealed a negative correlation between the consumption of tomatoes and tomato products or circulating levels of lycopene with risk.
Research by Langner et al. found that tomato juice rich in lycopene (17 mg/L) had an inhibitory effect on colon in rat models, reducing the occurrence of bladder transitional cell carcinoma in male rats. Moreover, adding lycopene to drinking water (50 mg/L) also had an inhibitory effect on lung disease in male mice.
03. Research on cardiovascular health
The "2021 Report on Cardiovascular Wellbeing and Illness in China" delivered by the Public Cardiovascular Sickness Community shows that there are 330 million individuals experiencing cardiovascular infections in China, including 8.9 million cardiovascular breakdown patients. Cardiovascular well-being is getting expanding consideration. Research shows that lycopene can bring down blood cholesterol and fatty oil levels, safeguard low-thickness lipoproteins from oxidation, fix oxidized cells speedily, advance the development of interstitial cells, subsequently work on the general sturdiness of veins, widening veins, diminishing circulatory strain, hindering platelet collection, and forestalling apoplexy.
Concentrates by Qin Wei et al. in bunny models of atherosclerosis prompted by a high-fat eating regimen and directed lycopene at 50 mg/kg for 40 successive days showed critical restraint of aortic and heart low-thickness lipoprotein receptor mRNA articulation and diminished serum fatty substance levels, successfully lightening atherosclerotic sores. Jiang H et al. found a negative relationship between's plasma lycopene levels and the thickness and harm of the carotid and aortic vessel walls, successfully forestalling the improvement of atherosclerosis. The lipid oxidation of LDL is critical consider the improvement of atherosclerosis, and lycopene's lipid-bringing impact is connected down to its capacity to hinder DNA and lipoprotein oxidation, as well as forestalling the development of LDL cholesterol oxidation items.
Stability Defect of Natural Lycopene Powder
Settling the solidness deformity of lycopene powder requires a deliberate methodology and a comprehension of the variables influencing its dependability. Here are a few stages you can take to quickly address the soundness issues:
1. Identify the stability issue: Begin by understanding the specific stability problem with your natural powder. Oxidation, light sensitivity, temperature sensitivity, moisture absorption, or chemical interactions are a few examples of stability problems.
2. Analyze the formulation: Evaluate the formulation to determine if any ingredients are contributing to the stability issues. Consider the carrier materials, antioxidants, stabilizers, and other excipients used in the product.
3. Review processing methods: Examine the manufacturing processes involved in producing the lycopene powder. Sometimes, stability issues can arise due to improper processing methods or exposure to unfavorable conditions during production.
4. Conduct stability testing: Perform accelerated stability tests on the lycopene under various conditions, such as temperature, humidity, light exposure, and pH levels. This will help you identify the factors that lead to the stability defect and understand the shelf-life of the product. Proposed schemes to improve the stability of lycopene have shown that under light-sealed conditions at 4°C, the content retention rate of lycopene can exceed 85% when using the microencapsulation technology.
5. Optimize packaging: Evaluate the packaging material and design to ensure it provides adequate protection from environmental factors such as light, oxygen, and moisture.
6. Modify storage conditions: Establish proper storage conditions based on the stability testing results. This may involve storing the powder in a cool, dry, and dark place or using temperature-controlled storage.
References:
[1] Fan Yuanjing, Huang Lu. A study on the absorption and in vivo antioxidant mechanisms of lycopene. Food Science, 2007, 28(11): 545-548.
[2] Qin Wei, Qian Yan. The influence of lycopene on blood lipids and low-density lipoprotein receptor mRNA expression in rabbits with atherosclerosis induced by a high-fat diet. Chinese Journal of Hospital Pharmacy, 2010, 30(3): 191-194.
[3] Jiang H Q, Wang Z Z, Ma Y, et al. Effect of dietary lycopene supplementation on growth performance, meat quality, fatty acid profile, and meat lipid oxidation in lambs in summer conditions. Small Ruminant Research, 2015, 131: 99-106.
[4] Peng Liang, Zhao Peng, Li Bin, et al. Safety and antioxidant effects of lycopene on the human body. Chinese Journal of Public Health, 2012, 28(11): 1475-1476.
[5] The influence of processing technology on the physicochemical properties and antioxidant activity of lycopene microcapsules. Food and Fermentation Industries, 2023.