PART 01: Copper Elements and Peptides- GHK-Cu Powder
◆Copper
Obviously, Copper is a fundamental follow supplement for supporting natural cycles and general well-being, It is significant for the turn of events and activity of a few body frameworks, including the circulatory framework, immunological framework, focal sensory system, hair, skin, and bone tissue, as well as the mind, liver, and heart. In adults, the human body contains approximately 1.4mg to 2.1mg of copper per kilogram of body weight.
◆Peptides
Peptides are little atoms comprised of amino acids, which are all the more effectively consumed by the skin and make more articulated impacts.
In 1973, scientist Pickart isolated GHK from human serum and described it as a regulator of the extracellular matrix of various differentiating cell growth factors. The concentration of GHK in plasma is significantly correlated with the regenerative capacity of organisms.
In 1986, GHK began to be applied in the repair and treatment of human tissues.
In 1999, dermatologists found that bioactive divalent copper particles, involving GHK as a transporter, could work on the skin's porousness to copper particles, successfully helping their entrance into organic cells to apply physiological impacts.
◆GHK-Cu
The mix of copper and peptides, known as a copper peptide, settles copper particles, shipping them to the skin for fixing harm and advancing enzymatic responses. This synergistic impact likewise helps with the blend of collagen antecedents, upgrading skin flexibility and further developing the skin surface.
blue copper peptide: GHK-Cu
G (Glycine)
H (Histidine)
K (Lysine)
These three amino acids combined form a tripeptide, which is then linked to a copper ion, creating the commonly known blue copper peptide. Its INCI name/English name is Copper Tripeptide-1 (COPPER TRIPEPTIDE-1).
With the presence of copper ions, its efficacy is greatly enhanced. Since copper ions are essential for numerous enzymatic reactions in the body, Tripeptide-1 acts as a carrier, effectively delivering copper ions into cells to exert their effects.
Worth mentioning is that due to its high cost, it is referred to as the "blue gold" of the skincare industry, with a market price exceeding 100,000 yuan per kilogram.
PART 02. Benefits
GHK-Cu Powder components are gentle and safe, and offer a non-irritating user experience that is unparalleled by other ingredients. It provides daytime antioxidant protection and repairs photodamage, offering a gentle yet potent anti-aging solution.
1. Anti-Aging and Wrinkle Reduction:
GHK-Cu promotes the generation of glycosaminoglycans (GAGs), important components of the extracellular matrix that keep the skin plump, hydrated, and elastic.
2. Anti-Inflammatory and Antibacterial:
Its reparative function is evident. It effectively promotes wound healing and regeneration, repairs damaged skin, and inhibits the synthesis of various inflammatory factors, reducing the occurrence of acne and inflammation. As a result, it is highly effective in helping the skin recover after exfoliation.
3. Antioxidant and Brightening:
Oxidation caused by external environmental stimuli is a major contributor to skin aging. The "copper" carried by blue copper peptide strengthens the skin's antioxidant function. It can repress the arrangement of responsive oxygen species, dispose of different peroxides, shield keratinocytes from UV harm, light up the composition, refine the skin, and forestall skin maturing.
PART 03: Challenges of Blue Copper Peptide
Many domestic brands have launched products featuring GHK-Cu as a key ingredient. However, its high price, reaching hundreds of thousands of yuan per kilogram, makes it comparable to the "Hermès of skincare."
1. Expensive Price:
Its market price exceeds 100,000 yuan per kilogram, making it prohibitively costly for most brands.
2. Difficult Compatibility:
Due to the presence of copper metal ions, this ingredient becomes delicate and may be deactivated by many other effective ingredients, such as acid compounds (glycolic acid, salicylic acid), antioxidants, and whitening agents (niacinamide and vitamin C).
3. Why Did GHK-Cu Become Popular:
Its repairing mechanism mainly targets the basement membrane structure, promotes the revitalization of damaged cells, and stimulates the production of extracellular matrix. It somewhat resembles the action of Bose-Einstein condensate (Bose-Einstein condensate is a phenomenon in physics). With more people experiencing sensitive skin, there is a genuine need for gentle and effective anti-aging products, which happens to be a specialty of blue copper peptides.
4. Why is it Blue:
It's composed of copper ions and Tripeptide-1. When combined in a solution, it appears blue. The darker the color, the higher the concentration, leading to more pronounced effects on the skin.
PART 04. Is it true that using blue copper peptide can cause the skin to darken?
Currently, there is no relevant human data to support this claim!
1.No English literature indicates that copper peptides affect melanocytes.
2. Human data shows that using GHK-Cu preparations for 12 weeks can significantly reduce skin pigmentation, resulting in a more even skin tone.
3. Zhang Yunfei's master's thesis from Dalian Medical University shows that copper peptides have an upregulating effect on mushroom tyrosinase and melanocytes. However, animal experimental data is insufficient and needs to exclude inflammation as a factor affecting melanocyte activation.
This data cannot be used as evidence for "skin darkening."
PART 05. GHK-Cu Usage Precautions
Please remember:
1. Avoid using it simultaneously with high-concentration acid compounds (glycolic acid, lactic acid, salicylic acid), as this can deactivate copper ions.
2. Avoid simultaneous use of retinol (vitamin A), as it may increase melanin production.
3. Avoid simultaneous use of vitamin C, as it may lead to a reduction reaction and render both ineffective.
4. Avoid simultaneous use with emulsifiers/polymers, as it may lead to precipitation, and pilling, and affect user experience.
5. Try to use it alone.
6. There's no need to pursue high concentrations; a concentration of 0.01% to 0.2% is effective against aging.
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