When to Take HCA Best?
There is a view that the efficacy of Hydroxycitric Acid depends on the time of ingestion. Although the activity of HCA can be maintained when taken a few hours after a meal, Garcinia Cambogia Extract Powder HCA is most effective when taken 30-60 minutes before a meal. In most clinical trials, HCA was taken 30 minutes before meals. This is low in the most effective time frame.
However, there are also experiments showing that the respiratory quotient (RQ) tends to be lower when HCA is taken after meals, although the trend is not very obvious.
Experiments show that the absorption rate of HCA taken on an empty stomach is higher than that taken with meals, so the bioavailability is also higher. Moreover, the effect of taking HCA in divided doses is better than that of taking HCA at one time. Experiments show that taking HCA 2 to 3 times a day is 7 times more effective than taking it once a day.
Hydroxycitric Acid Dosage For Weight Loss
The effective intake dose of HCA is currently unknown. According to the optimal micromolar concentration (300mmol/L) of HCA required to activate the highest level of 5-HT in the cerebral cortex of mice, the effective intake dose of HCA was determined to be about 2,800mg/d.
Consuming a low-fat meal at the same time as taking HCA can enhance its weight loss effect. Because HCA does not reduce the energy of dietary fat
quantity. Since one possible mechanism of action of HCA is to inhibit the conversion of simple sugars to fat, HCA works best when combined with a diet rich in simple sugars.
Who Shouldn't Take Hydroxycitric Acid?
Because Garcinia Cambogia Extract can affect the body's fatty acid and cholesterol synthesis. And it may directly affect sterol production and limit the production of steroid hormones. Women are very sensitive to steroid hormones during pregnancy, so it is not suitable for consumption at this time. Likewise, women who are breastfeeding should also avoid HCA.
There is also a view that the promoting effect of HCA on gluconeogenesis and ketosis is not beneficial to diabetics. But the good weight loss effect of HCA on obese non-insulin-dependent diabetes mellitus exceeds its negative effect, and the advantages outweigh the disadvantages.
In addition, although long-term consumption of HCA-rich fruits has not been shown to cause any harm to children, it is still recommended that children do not consume excessive amounts in the long term.